KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKL3
All Species:
16.36
Human Site:
S395
Identified Species:
27.69
UniProt:
Q8IVW4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVW4
NP_001107047.1
592
67514
S395
N
E
N
V
H
P
M
S
P
D
T
K
L
V
T
Chimpanzee
Pan troglodytes
XP_517934
592
67566
S395
N
E
N
V
H
P
M
S
P
D
T
K
L
V
T
Rhesus Macaque
Macaca mulatta
XP_001108660
592
67612
S395
N
E
N
V
H
P
M
S
P
D
T
K
L
V
T
Dog
Lupus familis
XP_850612
456
51739
H283
S
S
T
D
L
L
H
H
E
Y
F
T
R
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLF2
595
67720
S397
A
D
D
T
Q
P
S
S
L
D
K
K
P
S
V
Rat
Rattus norvegicus
Q9JM01
593
67534
S397
A
E
D
T
H
P
T
S
L
D
R
K
P
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512927
637
71445
L396
N
F
L
P
L
Q
D
L
K
P
A
D
T
E
L
Chicken
Gallus gallus
P13863
303
34670
K130
R
V
L
H
R
D
L
K
P
Q
N
L
L
I
D
Frog
Xenopus laevis
P35567
302
34487
L129
R
R
V
L
H
R
D
L
K
P
Q
N
L
L
I
Zebra Danio
Brachydanio rerio
Q6AXJ9
350
40792
T177
P
E
L
L
V
G
D
T
Q
Y
G
P
P
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
V124
L
F
C
H
R
R
R
V
L
H
R
D
L
K
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784044
926
104004
S414
G
P
S
I
Q
S
I
S
S
S
S
K
L
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
H121
G
V
A
Y
C
H
S
H
R
V
L
H
R
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
H121
G
I
A
Y
C
H
S
H
R
V
L
H
R
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
67.7
N.A.
80.5
79
N.A.
57.7
25
24.3
31
N.A.
23.4
N.A.
N.A.
30.2
Protein Similarity:
100
99.8
99.6
72.1
N.A.
89.7
87.6
N.A.
68.9
34.9
35.6
43
N.A.
35.1
N.A.
N.A.
44
P-Site Identity:
100
100
100
0
N.A.
26.6
40
N.A.
6.6
13.3
13.3
13.3
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
100
6.6
N.A.
40
46.6
N.A.
6.6
26.6
26.6
26.6
N.A.
6.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
22.8
N.A.
23.1
N.A.
N.A.
Protein Similarity:
N.A.
33.9
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
15
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
8
0
15
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
15
8
0
8
22
0
0
36
0
15
0
22
15
% D
% Glu:
0
36
0
0
0
0
0
0
8
0
0
0
0
8
0
% E
% Phe:
0
15
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
22
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
15
36
15
8
22
0
8
0
15
0
0
0
% H
% Ile:
0
8
0
8
0
0
8
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
8
15
0
8
43
0
8
0
% K
% Leu:
8
0
22
15
15
8
8
15
22
0
15
8
50
8
22
% L
% Met:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% M
% Asn:
29
0
22
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
8
8
0
8
0
36
0
0
29
15
0
8
22
8
8
% P
% Gln:
0
0
0
0
15
8
0
0
8
8
8
0
0
0
8
% Q
% Arg:
15
8
0
0
15
15
8
0
15
0
15
0
22
0
0
% R
% Ser:
8
8
8
0
0
8
22
43
8
8
8
0
0
15
0
% S
% Thr:
0
0
8
15
0
0
8
8
0
0
22
8
8
0
22
% T
% Val:
0
15
8
22
8
0
0
8
0
15
0
0
0
29
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
0
0
0
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _